CALL FOR PAPERS Innovative and Emerging Technologies in GI Physiology and Disease Ex vivo perfusion of the isolated rat small intestine as a novel model of Salmonella enteritis
نویسندگان
چکیده
Erin C. Boyle, Heike Dombrowsky, Jürgen Sarau, Janin Braun, Martin Aepfelbacher,* Ingmar Lautenschläger,* and Guntram A. Grassl* Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Bernhard Nocht Institute of Tropical Medicine, Hamburg, Germany; Priority Area Asthma and Allergy, Research Center Borstel, Borstel, Germany; Priority Area Infections, Models of Inflammation, Research Center Borstel, Borstel, Germany; Institute for Experimental Medicine, Christian-Albrechts University Kiel, Kiel, Germany; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Kiel, Germany; and Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School and German Center for Infection Research (DZIF), Hannover, Germany
منابع مشابه
Ex vivo perfusion of the isolated rat small intestine as a novel model of Salmonella enteritis.
Using an ex vivo perfused rat small intestinal model, we examined pathological changes to the tissue, inflammation induction, as well as dynamic changes to smooth muscle activity, metabolic competence, and luminal fluid accumulation during short-term infection with the enteropathogenic bacteria Salmonella enterica serovar Typhimurium and Yersinia enterocolitica. Although few effects were seen u...
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تاریخ انتشار 2016